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J Clin Endocrinol Metab. 1989 Sep;69(3):689-91.

Depot leuprolide acetate for treatment of precocious puberty.

Author information

1
Department of Pediatrics, University of Pittsburgh School of Medicine, Pennsylvania.

Abstract

Leuprolide acetate (D-Leu 6 des-Gly-NH2(10), Pro-ethylamide9) for depot suspension has been shown to be effective in suppressing gonadotropins in 6 patients. Serum LH and FSH response to exogenous LHRH was obliterated after 4 weeks and weekly urinary gonadotropin levels during depot therapy were suppressed. This form of this drug should be effective in the treatment of precocious puberty.

PMID:
2503536
DOI:
10.1210/jcem-69-3-689
[Indexed for MEDLINE]

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