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Neuron. 2014 Jul 16;83(2):253-254. doi: 10.1016/j.neuron.2014.07.008.

MicroRNA-mediated repression combats depression.

Author information

1
Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029-6574, USA.
2
Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029-6574, USA. Electronic address: paul.kenny@mssm.edu.

Erratum in

  • Neuron. 2014 Aug 6;83(3):749.

Abstract

Precisely how SSRIs induce long-term modifications in serotonin transmission to elicit their antidepressant actions is unclear. In this issue of Neuron, Issler et al. (2014) identify a key role for microRNA-135a [corrected] in the raphe nuclei in the molecular mechanisms underlying the therapeutic actions of SSRIs.

PMID:
25033172
DOI:
10.1016/j.neuron.2014.07.008
[Indexed for MEDLINE]
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