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Kidney Int Suppl (2011). 2011 Jun;1(1):21-23.

Cardiovascular and non-cardiovascular mortality in dialysis patients: where is the link?

Author information

1
ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam , Amsterdam, The Netherlands.
2
Department of Clinical Science, Intervention and Technology, Karolinska Institutet , Stockholm, Sweden.
3
Renal Unit, Guy's and St Thomas' NHS Foundation Hospital, King's Health Partners , London, UK.
4
Department of Internal Medicine IV, Saarland University Medical Centre , Homburg/Saar, Germany.
5
Division of Internal Medicine and Nephrology, Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia , Katowice, Poland.
6
Nephrology Division, Department of Medicine, Akdeniz University Medical School , Antalya, Turkey.
7
IIS-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo , Madrid, Spain.
8
INSERM ERI-12 (EA 4292) , Amiens, France ; Amiens University Hospital and the Jules Verne University of Picardie , Amiens, France.
9
Hospital Universitario de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Barcelona, Spain.
10
Indiana University and VAMC , Indianapolis, Indiana, USA.
11
Department of Nephrology, University Medical Center , Utrecht, The Netherlands.
12
C.I. Parhon University Hospital and Gr. T. Popa University of Medicine and Pharmacy , Iasi, Romania.
13
INSERM U970, Hôpital Européen Georges Pompidou , Paris, France.
14
Nephrology, Dialysis and Transplantation Unit and CNR-IBIM Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension , Reggio Calabria, Italy.
15
Department of Clinical Epidemiology, Leiden University Medical Center , Leiden, The Netherlands.

Abstract

Over the past decade, the research agenda in dialysis has been dominated by studies on risk factors associated with cardiovascular mortality. It has now become increasingly clear that in dialysis patients, non-cardiovascular causes of death are increased to the same extent as cardiovascular mortality, and therefore research efforts in this area deserve an equally prominent place on the nephrology research agenda. As previous research has suggested an association between cardiovascular disease and infections, more research on potential links between the causal pathways of cardiovascular events and infections is also warranted.

KEYWORDS:

cardiovascular disease; cardiovascular mortality; dialysis; mortality; non-cardiovascular mortality; renal replacement therapy

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