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Stroke. 2014 Sep;45(9):2795-7. doi: 10.1161/STROKEAHA.114.006144. Epub 2014 Jul 15.

Morphology of susceptibility vessel sign predicts middle cerebral artery recanalization after intravenous thrombolysis.

Author information

1
From the Department of Neurology, the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China (S.Y., H.H., X.Z., S.Z., M.L.); Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China (Z.S.); and University of California-Los Angeles Stroke Center (D.S.L.).
2
From the Department of Neurology, the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China (S.Y., H.H., X.Z., S.Z., M.L.); Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China (Z.S.); and University of California-Los Angeles Stroke Center (D.S.L.). loumingxc@vip.sina.com.

Abstract

BACKGROUND AND PURPOSE:

We aimed to evaluate the predictive value of susceptibility vessel sign (SVS) burden and morphology in middle cerebral artery recanalization.

METHODS:

We retrospectively examined clinical and imaging data from 72 consecutive patients with acute ischemic stroke with middle cerebral artery occlusion and examined the association of recanalization with SVS length and shape.

RESULTS:

None of the patients with a middle cerebral artery SVS >20 mm in length achieved recanalization. For patients with a relatively short SVS (length <20 mm), irregular shape was a strong independent predictor for no recanalization (odds ratio, 6.891; 95% confidence interval, 1.441-32.950; P=0.016).

CONCLUSIONS:

Irregular shape and long length (>20 mm) of SVS decrease the potential to recanalize the occluded middle cerebral artery with intravenous thrombolysis.

KEYWORDS:

magnetic resonance imaging; middle cerebral artery; stroke; thrombolytic therapy

PMID:
25028445
DOI:
10.1161/STROKEAHA.114.006144
[Indexed for MEDLINE]

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