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Eur Rev Med Pharmacol Sci. 2014;18(14):2070-5.

Lunasin as a promising health-beneficial peptide.

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1
College of Health Science, Wuhan Sports University, Wuhan, China. chenning@wipe.edu.cn.

Abstract

Lunasin, a 43 amino acid polypeptide originally isolated from soybean, is known to produce multiple health benefits, including anti-hypertension, antioxidant activity, cancer prevention or therapy, anti-inflammation, hypocholesterolemic activity, anti-obesity and immunomodulation. These effects are believed to be due to its unique structure that includes a putative helical region, an Arg-Gly-Asp (RGD) motif and an Asp-rich carboxyl terminus. The focus of this article is to summarize the discovery, characterization and biological activities of lunasin, which will provide a reference for the future development and utilization of lunasin, and a basis for exploring the underlying mechanisms of these health-beneficial functions.

PMID:
25027349
[Indexed for MEDLINE]
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