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Curr Treat Options Neurol. 2014 Sep;16(9):306. doi: 10.1007/s11940-014-0306-5.

Current understanding of chronic traumatic encephalopathy.

Baugh CM1,2, Robbins CA1, Stern RA#1,2,3,4, McKee AC#1,2,4,5,6.

Author information

1
Boston University School of Medicine, CTE Center, Boston University School of Medicine, 72 E. Concord Street, Suite B7800, Boston, MA 02118, USA.
2
Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
3
Department of Neurosurgery, Boston University School of Medicine, Boston, MA, USA.
4
Boston University Alzheimer's Disease Center, Boston, MA, USA.
5
Department of Pathology, Boston University School of Medicine, Boston, MA, USA.
6
VA Boston Healthcare System, Boston, MA, USA.
#
Contributed equally

Abstract

Chronic traumatic encephalopathy (CTE) is a unique neurodegenerative disease found in individuals with a history of repetitive head impacts. The neuropathology of CTE is increasingly well defined. Prospective, longitudinal studies with post-mortem neuropathologic validation as well as in vivo diagnostic techniques are needed in order to advance the understanding of CTE clinically. Given the large number of individuals who incur concussions and other forms of brain trauma, this is an important area for scientific and public health inquiry.

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