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C R Acad Sci III. 1989;309(2):43-7.

[L-tyrosine: a long term treatment of Parkinson's disease].

[Article in French]

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Unité clinique de Psychiatrie biologique, C.H.S. Le Vinatier, Lyon-Bron.


That l-dopa represents a major advance in Parkinson treatment should not hide that a number of problems remain unanswered: on-off effects, transient improvements... Based on the beneficial effects of l-tyrosine in dopamine dependent depressions and narcolepsy, five naive patients diagnosed after sleep polygraphy criteria and five l-dopa and/or dopamine agonist treated patients were prescribed l-tyrosine as a long-term treatment. For some patients, 3 years of L-tyrosine treatment was followed by better clinical results and many fewer side effects than with L-DOPA or dopamine agonists. However, the theoretical long-term sparing neurons potentiality of approach requires further studies.

[Indexed for MEDLINE]

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