Format

Send to

Choose Destination
Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Jun;89(6):062706. Epub 2014 Jun 13.

Torque correlation length and stochastic twist dynamics of DNA.

Author information

1
Department of Physics and Astronomy, Northwestern University, Evanston, Illinois 60208, USA.
2
Department of Physics and Astronomy, Northwestern University, Evanston, Illinois 60208, USA and Department of Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, USA.

Abstract

We introduce a short correlation length for torque in twisting-stiff biomolecules, which is necessary for the physical property that torque fluctuations be finite in amplitude. We develop a nonequilibrium theory of dynamics of DNA twisting which predicts two crossover time scales for temporal torque correlations in single-molecule experiments. Bending fluctuations can be included, and at linear order we find that they do not affect the twist dynamics. However, twist fluctuations affect bending, and we predict the spatial inhomogeneity of twist, torque, and buckling arising in nonequilibrium "rotor-bead" experiments.

PMID:
25019813
PMCID:
PMC4141913
DOI:
10.1103/PhysRevE.89.062706
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center