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Chem Commun (Camb). 2014 Sep 4;50(68):9733-6. doi: 10.1039/c4cc04015e.

An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime.

Author information

1
Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands. f.w.b.van_leeuwen@lumc.nl.

Abstract

In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging.

PMID:
25019263
DOI:
10.1039/c4cc04015e
[Indexed for MEDLINE]

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