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Clin Pediatr (Phila). 2014 Dec;53(14):1375-82. doi: 10.1177/0009922814541804. Epub 2014 Jul 8.

Growth of healthy term infants fed partially hydrolyzed whey-based infant formula: a randomized, blinded, controlled trial.

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Abbott Nutrition, Abbott Laboratories, Columbus, OH, USA
Abbott Nutrition, Abbott Laboratories, Columbus, OH, USA.


Partially hydrolyzed formulas (pHF) represent a significant percentage of the infant formula market. A new whey-based, palm olein oil (PO)-free pHF was developed and a masked, randomized, parallel growth study was conducted in infants fed this formula or a commercially available whey-based pHF with PO. Infants between 0 and 8 days were to be enrolled and studied to 119 days of age. Growth and tolerance of infants were evaluated. Mean weight gain from 14 to 119 days of age was similar between groups. There were no significant differences between groups in weight, length, head circumference (HC), or length or HC gains. Infants fed the new PO-free pHF had significantly softer stools than those fed the PO-containing formula except at 119 days of age. This study demonstrates that whereas growth of infants fed different formulas during the first 4 months of life may be similar, infants may tolerate individual formulas differently.


hydrolysate formula; infant feeding; infant formula; infant growth; weight

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