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J R Soc Interface. 2014 Sep 6;11(98):20140601. doi: 10.1098/rsif.2014.0601.

Influence of inhomogeneous static magnetic field-exposure on patients with erosive gastritis: a randomized, self- and placebo-controlled, double-blind, single centre, pilot study.

Author information

1
2nd Department of Internal Medicine, Semmelweis University, Budapest, Szentkirályi u. 46, 1088, Hungary.
2
e-Comers LLC, Csejtei u. 1-3, Budapest 1025, Hungary Department of Computer Science, University of Debrecen, Kassai út 26, Debrecen 4028, Hungary laszlo.janos@inf.unideb.hu.

Abstract

This pilot study was devoted to the effect of static magnetic field (SMF)-exposure on erosive gastritis. The randomized, self- and placebo-controlled, double-blind, pilot study included 16 patients of the 2nd Department of Internal Medicine, Semmelweis University diagnosed with erosive gastritis. The instrumental analysis followed a qualitative (pre-intervention) assessment of the symptoms by the patient: lower heartburn (in the ventricle), upper heartburn (in the oesophagus), epigastric pain, regurgitation, bloating and dry cough. Medical diagnosis included a double-line upper panendoscopy followed by 30 min local inhomogeneous SMF-exposure intervention at the lower sternal region over the stomach with peak-to-peak magnetic induction of 3 mT and 30 mT m(-1) gradient at the target site. A qualitative (post-intervention) assessment of the same symptoms closed the examination. Sham- or SMF-exposure was used in a double-blind manner. The authors succeeded in justifying the clinically and statistically significant beneficial effect of the SMF- over sham-exposure on the symptoms of erosive gastritis, the average effect of inhibition was 56% by p = 0.001, n = 42 + 96. This pilot study was aimed to encourage gastroenterologists to test local, inhomogeneous SMF-exposure on erosive gastritis patients, so this intervention may become an evidence-based alternative or complementary method in the clinical use especially in cases when conventional therapy options are contraindicated.

KEYWORDS:

double-blind; erosive gastritis; pilot study; randomized; self- and placebo-controlled; static magnetic field-exposure

PMID:
25008086
PMCID:
PMC4233709
DOI:
10.1098/rsif.2014.0601
[Indexed for MEDLINE]
Free PMC Article

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