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ACS Appl Mater Interfaces. 2014 Sep 24;6(18):15611-25. doi: 10.1021/am5008479. Epub 2014 Jul 16.

Coatings and films made of silk proteins.

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Lehrstuhl Biomaterialien, Fakultät für Ingenieurwissenschaften, ‡Bayreuther Zentrum für Kolloide und Grenzflächen (BZKG), §Institut für Bio-Makromoleküle (bio-mac), ∥Bayreuther Zentrum für Molekulare Biowissenschaften (BZMB), and ⊥Bayreuther Materialzentrum (BayMAT), Universität Bayreuth , Universitätsstrasse 30, 95440 Bayreuth, Germany.


Silks are a class of proteinaceous materials produced by arthropods for various purposes. Spider dragline silk is known for its outstanding mechanical properties, and it shows high biocompatibility, good biodegradability, and a lack of immunogenicity and allergenicity. The silk produced by the mulberry silkworm B. mori has been used as a textile fiber and in medical devices for a long time. Here, recent progress in the processing of different silk materials into highly tailored isotropic and anisotropic coatings for biomedical applications such as tissue engineering, cell adhesion, and implant coatings as well as for optics and biosensors is reviewed.


biomedical application; biosensor; optics; processing; silkworm silk; spider silk

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