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Curr Biol. 2014 Jul 7;24(13):R605-7. doi: 10.1016/j.cub.2014.05.059.

Nuclear envelope breakdown: actin' quick to tear down the wall.

Author information

1
MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.
2
MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. Electronic address: mschuh@mrc-lmb.cam.ac.uk.

Abstract

Nuclear envelope breakdown in metazoan cells is thought to be facilitated by microtubules, which pull on the nuclear membranes. Unexpectedly, an F-actin meshwork helps to tear down the large nucleus of starfish oocytes and to prevent chromosome loss in meiosis.

PMID:
25004364
DOI:
10.1016/j.cub.2014.05.059
[Indexed for MEDLINE]
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