Cells as delivery vehicles for cancer therapeutics

Ther Deliv. 2014 May;5(5):555-67. doi: 10.4155/tde.14.24.

Abstract

Cell-based therapeutics have advanced significantly over the past decade and are poised to become a major pillar of modern medicine. Three cell types in particular have been studied in detail for their ability to home to tumors and to deliver a variety of different payloads. Neural stem cells, mesenchymal stem cells and monocytes have each been shown to have great potential as future delivery systems for cancer therapy. A variety of other cell types have also been studied. These results demonstrate that the field of cell-based therapeutics will only continue to grow.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Drug Delivery Systems*
  • Humans
  • Mesenchymal Stem Cells / metabolism*
  • Monocytes / metabolism*
  • Neoplasms / drug therapy*
  • Neural Stem Cells / metabolism*