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Head Neck. 2016 Jan;38(1):15-20. doi: 10.1002/hed.23838. Epub 2015 Jan 27.

Value of narrow band imaging in the early diagnosis of laryngeal cancer.

Author information

1
Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital Baselland, Liestal, Switzerland.
2
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Basel, Basel, Switzerland.
3
Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital AG, Aarau, Switzerland.
4
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Magdeburg, Magdeburg, Germany.

Abstract

BACKGROUND:

Narrow band imaging (NBI) is a new imaging technique for the depiction of tumor-specific neoangiogenesis. The purpose of the present study was to assess the value of NBI in the early diagnosis of laryngeal cancer.

METHODS:

This prospective study includes 205 consecutive patients with a laryngeal lesion scheduled for microlaryngoscopy. NBI was immediately performed after white light endoscopy (WLE), whereas excisional biopsy was carried out for histologic verification of diagnosis.

RESULTS:

In identifying laryngeal cancer and its precursor lesions, NBI with WLE showed a significantly higher sensitivity (97% vs 79%) and accuracy (97% vs 90%) than WLE alone, but the specificity (96% vs 95%) was essentially equal in both methods.

CONCLUSION:

NBI qualifies for rapid detection and delineation of suspicious lesions. Additionally, this noninvasive method is also beneficial in a variety of benign lesions.

KEYWORDS:

cancer; diagnostic imaging; dysplasia; endoscopy; indirect laryngoscopy; laryngology; larynx; narrow band imaging; vocal fold

PMID:
24995546
DOI:
10.1002/hed.23838
[Indexed for MEDLINE]

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