Format

Send to

Choose Destination
Curr Opin Microbiol. 2014 Jun;19:25-29. doi: 10.1016/j.mib.2014.06.001. Epub 2014 Jul 1.

Antibiotic resistance gene discovery in food-producing animals.

Author information

1
Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA 50010, USA. Electronic address: heather.allen@ars.usda.gov.

Abstract

Numerous environmental reservoirs contribute to the widespread antibiotic resistance problem in human pathogens. One environmental reservoir of particular importance is the intestinal bacteria of food-producing animals. In this review I examine recent discoveries of antibiotic resistance genes in agricultural animals. Two types of antibiotic resistance gene discoveries will be discussed: the use of classic microbiological and molecular techniques, such as culturing and PCR, to identify known genes not previously reported in animals; and the application of high-throughput technologies, such as metagenomics, to identify novel genes and gene transfer mechanisms. These discoveries confirm that antibiotics should be limited to prudent uses.

PMID:
24994584
DOI:
10.1016/j.mib.2014.06.001
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center