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Antibiot Khimioter. 1989 Jan;34(1):3-6.

[Lipids of initial and mutant cultures of Penicillium chrysogenum, producers of penicillin].

[Article in Russian]


Comparative investigation of lipogenesis in 2 initial and 4 mutant strains of Penicillium chrysogenum showed that there were no noticeable differences in the composition of the lipid fatty acids in these strains. Certain shifts in the ratio of definite lipid fatty acids in the mutant strain deficient by synthesis of lysine and isoleucine (increased contents of oleic acid) were revealed. A marked influence of the physiological conditions on lipogenesis in the mutant with multiple deficiency by amino acids, vitamins and nucleotides was observed.

[Indexed for MEDLINE]

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