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Cell Metab. 2014 Jul 1;20(1):2-4. doi: 10.1016/j.cmet.2014.06.007.

Rejuvenation: it's in our blood.

Author information

1
Department of Pathology, University of Washington, Seattle, WA 98195-7470, USA.
2
Department of Pathology, University of Washington, Seattle, WA 98195-7470, USA. Electronic address: kaeber@uw.edu.

Abstract

It has been known for some time that blood from young mice can positively impact aged animals, while blood from old mice has the opposite effect. Recent studies report that rejuvenating effects of young blood extend to multiple tissues and have identified GDF11 and CCL11 as factors mediating these effects.

PMID:
24988454
PMCID:
PMC4126586
DOI:
10.1016/j.cmet.2014.06.007
[Indexed for MEDLINE]
Free PMC Article

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