The mutagenicity of refuse leachate from a municipal incinerator

Sci Total Environ. 1989 Jan:78:131-45. doi: 10.1016/0048-9697(89)90027-2.

Abstract

The mutagenicity of refuse leachate from a municipal incinerator was studied by liquid rec-assay and Ames assay. Volatile components were found to be negative, and nonvolatile components positive, in the Ames assay and the leachate was found to have DNA-damaging capacity in the liquid rec-assay with S-9 mix. PAHs derived from tobacco ash and carbonyl compounds generated by the putrefaction of foods were confirmed to be main contributors to DNA-damaging capacity and mutagenicity in refuse leachate.

MeSH terms

  • Animals
  • Bacillus subtilis / drug effects
  • Biotransformation
  • DNA Damage
  • Humans
  • Japan
  • Microsomes, Liver / metabolism
  • Mutagenicity Tests
  • Mutagens / analysis*
  • Mutagens / pharmacology
  • Mutation*
  • Refuse Disposal*
  • SOS Response, Genetics
  • Salmonella typhimurium / drug effects
  • Salmonella typhimurium / genetics
  • Urban Population
  • Water Pollutants / analysis

Substances

  • Mutagens
  • Water Pollutants