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ISRN Nephrol. 2013 Sep 4;2013:898125. doi: 10.5402/2013/898125. eCollection 2013.

The pleiotropic effect of vitamin d.

Author information

1
Division of Nephrology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, No. 707, Section 3, Chung Yang Road, Hualien 97004, Taiwan.
2
Division of Nephrology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, No. 707, Section 3, Chung Yang Road, Hualien 97004, Taiwan ; School of Medicine, Tzu Chi University, Hualien, Taiwan ; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.

Abstract

The novel roles of vitamin D were discovered and valued in this century. In addition to the maintenance of calcium and phosphorus balance, vitamin D regulates the function of the kidneys, heart, and immune system. Moreover, its anti-inflammatory, antiapoptotic, and antifibrotic roles have gained considerable attention. Vitamin D is also important for the maintenance of homeostasis by regulation of hormone secretion, cell proliferation, and differentiation. This paper will review these pleiotropic functions of vitamin D.

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