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Am J Ophthalmol. 1989 May 15;107(5):511-4.

Treatment of gonococcal conjunctivitis with single-dose intramuscular ceftriaxone.

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Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, FL 33010.


We treated 13 consecutive patients with culture proven Neisseria gonorrhoeae conjunctivitis with single-dose intramuscular injections of ceftriaxone. Pretreatment conjunctival cultures and Gram stains were obtained from all patients. The patients were admitted for antibiotic administration, a single conjunctival saline lavage, and follow-up conjunctival cultures six and 12 hours after treatment. Three of 13 organisms (23%) were penicillinase producing. All patients responded to treatment, and all six- and 12-hour posttreatment cultures were negative for N. gonorrhoeae. These results indicate that a single intramuscular dose of ceftriaxone is curative treatment for non-neonatal gonococcal conjunctivitis.

[Indexed for MEDLINE]

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