Format

Send to

Choose Destination
J Int Neuropsychol Soc. 2014 Jul;20(6):588-98. doi: 10.1017/S1355617714000241. Epub 2014 Jun 24.

Reliability and validity of composite scores from the NIH Toolbox Cognition Battery in adults.

Author information

1
1Department of Psychiatry,University of California,San Diego,California.
2
2Departments of Rehabilitation Medicine,Orthopedic Surgery, and General Medicine,New York University Langone Medical Center,New York; and Spinal Cord Injury,Kessler Foundation,West Orange,New Jersey.
3
3Department of Neurology,University of California,Davis,California.
4
4Cognitive Neurology and Alzheimer's Disease Center and Department of Psychiatry and Behavioral Sciences,Northwestern Feinberg School of Medicine,Chicago,Illinois.
5
5Department of Rehabilitation Medicine,University of Washington,Seattle,Washington.
6
6Department of Medical Social Sciences,Northwestern University,Chicago,Illinois.
7
7San Diego State University/University of California,San Diego Joint Doctoral Program in Clinical Psychology,San Diego,California.
8
8National Institute on Drug Abuse,Rockville,Maryland.

Abstract

This study describes psychometric properties of the NIH Toolbox Cognition Battery (NIHTB-CB) Composite Scores in an adult sample. The NIHTB-CB was designed for use in epidemiologic studies and clinical trials for ages 3 to 85. A total of 268 self-described healthy adults were recruited at four university-based sites, using stratified sampling guidelines to target demographic variability for age (20-85 years), gender, education, and ethnicity. The NIHTB-CB contains seven computer-based instruments assessing five cognitive sub-domains: Language, Executive Function, Episodic Memory, Processing Speed, and Working Memory. Participants completed the NIHTB-CB, corresponding gold standard validation measures selected to tap the same cognitive abilities, and sociodemographic questionnaires. Three Composite Scores were derived for both the NIHTB-CB and gold standard batteries: "Crystallized Cognition Composite," "Fluid Cognition Composite," and "Total Cognition Composite" scores. NIHTB Composite Scores showed acceptable internal consistency (Cronbach's alphas=0.84 Crystallized, 0.83 Fluid, 0.77 Total), excellent test-retest reliability (r: 0.86-0.92), strong convergent (r: 0.78-0.90) and discriminant (r: 0.19-0.39) validities versus gold standard composites, and expected age effects (r=0.18 crystallized, r=-0.68 fluid, r=-0.26 total). Significant relationships with self-reported prior school difficulties and current health status, employment, and presence of a disability provided evidence of external validity. The NIH Toolbox Cognition Battery Composite Scores have excellent reliability and validity, suggesting they can be used effectively in epidemiologic and clinical studies.

PMID:
24960398
PMCID:
PMC4103963
DOI:
10.1017/S1355617714000241
[Indexed for MEDLINE]
Free PMC Article

Publication type, MeSH terms, Grant support

Supplemental Content

Full text links

Icon for Cambridge University Press Icon for PubMed Central
Loading ...
Support Center