Send to

Choose Destination
Niger J Med. 2014 Apr-Jun;23(2):103-17.

Systematic review and metanalysis on community based interventions in tuberculosis care in developing countries.



We aimed to evaluate the effectiveness of Lay Health Workers (LHW) in increasing case detection rate and treatment success outcome of Tuberculosis cases


PUBMED,; Google scholar, African Journal Online (AJOL) and other search engines were systematically searched, for literature from 2000 to 2012 for studies that are either: [randomized/cluster randomized/non randomized or prospective cohort study); assessing lay Health care worker participation in tuberculosis (TB) treatment, using the key words (LHW, TB and treatment). Studies were pooled using a random effect model. Of the thirteen studies that fulfilled the inclusion criteria for systemic review, only five were heterogeneous enough for a meta-analysis.


There was a marginal effectiveness of LHW involvement in TB treatment success rate, RR 1.09 Confidence Interval. [0.98-1.21]. There was no publication bias; with {p = 0.135 for Eggar's weighed regression analysis}. Restrictive analysis showed a marginally higher summary relative risk in rural based studies RR 1.12, C.I. [1.01-1.24]; compared to urban studies RR 1.01, C.I. [0.91-1.13].


The use of Lay Health care workers is associated with a marginal benefit in improving TB treatment success compared to standard facility based TB care. Larger studies are needed to properly prove its superiority.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center