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Diagn Microbiol Infect Dis. 2014 Sep;80(1):32-4. doi: 10.1016/j.diagmicrobio.2014.05.019. Epub 2014 May 21.

Performance of the Cepheid Xpert® SA Nasal Complete PCR assay compared to culture for detection of methicillin-sensitive and methicillin-resistant Staphylococcus aureus colonization.

Author information

1
NorthShore University Health System, Evanston, IL. Electronic address: ppatel@northshore.org.
2
NorthShore University Health System, Evanston, IL.
3
NorthShore University Health System, Evanston, IL; University of Chicago Pritzker School of Medicine, Chicago, IL.

Abstract

Sensitivity, specificity, positive predictive value, and negative predictive value for the Cepheid Xpert® SA Nasal Complete detection (N = 971) of methicillin-sensitive Staphylococcus aureus was 86.5%, 98.5%, 94.6%, and 96.1%; detection of methicillin-resistant S. aureus was 89.3%, 97.9%, 79.8%, and 99.0%, respectively. Our results show that testing on long-term care facility patients had lower sensitivity and specificity compared to acute care patient results.

KEYWORDS:

MRSA; Methicillin-resistant Staphylococcus aureus; Rapid diagnostics; Real-time PCR; Staphylococcus aureus; Surveillance

[Indexed for MEDLINE]

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