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Cell. 2014 Jun 19;157(7):1738-1738.e1. doi: 10.1016/j.cell.2014.06.002.

SnapShot: receptor dynamics at plastic synapses.

Author information

1
University Medical Center Hamburg Eppendorf, Falkenried 94, 20251 Hamburg, Germany.
2
Ecole Normale Superieure, Institute of Biologie (IBENS) CNRS UMR 8197, Inserm 1024, 46 rue d'Ulm, Paris 75005, France.
3
Interdisciplinary Institute for Neurosciences, CNRS, Bordeaux University, UMR 5297, 146 rue Leo Saignat, 33077 Bordeaux, France.

Abstract

The dynamic synapse is represented by the constant mobility and exchange of components at both the cell surface and at intracellular sites. This includes thermally powered Brownian diffusion movement, followed by reversible trapping through receptor-scaffold interactions and active transport of cargo vesicles through cytoskeletal motors.

PMID:
24949980
DOI:
10.1016/j.cell.2014.06.002
[Indexed for MEDLINE]
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