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Genome Announc. 2014 Jun 19;2(3). pii: e00558-14. doi: 10.1128/genomeA.00558-14.

Genome Sequences of Two Carbapenemase-Resistant Klebsiella pneumoniae ST258 Isolates.

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Los Alamos National Laboratory, Los Alamos, New Mexico, USA.
University of North Carolina, Chapel Hill, North Carolina, USA.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
Center for Applied Biotechnology Studies, Department of Biological Science, California State University, Fullerton, Fullerton, California, USA


Klebsiella pneumoniae, an ESKAPE group (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogen, has acquired multiple antibiotic resistance genes and is becoming a serious public health threat. Here, we report the genome sequences of two representative strains of K. pneumoniae from the emerging K. pneumoniae carbapenemase (KPC) outbreak in northeast Ohio belonging to sequence type 258 (ST258) (isolates Kb140 and Kb677, which were isolated from blood and urine, respectively). Both isolates harbor a blaKPC gene, and strain Kb140 carries blaKPC-2, while Kb677 carries blaKPC-3.

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