Format

Send to

Choose Destination
Hong Kong Med J. 2014 Aug;20(4):325-30. doi: 10.12809/hkmj144243. Epub 2014 Jun 20.

Immunotherapy for peanut allergy.

Author information

1
Allergy Centre, Hong Kong Sanatorium and Hospital, 2 Village Road, Happy Valley, Hong Kong.
2
Department of Pathology, Hong Kong Sanatorium and Hospital, 2 Village Road, Happy Valley, Hong Kong.

Erratum in

  • Hong Kong Med J. 2014 Oct;20(5):400.

Abstract

Peanut allergy is one of the commonest food hypersensitivities causing fatal or near-fatal reactions. There is, currently, no preventive treatment and the incidence of severe allergic reactions during peanut desensitisation has limited its clinical use. Anti-immunoglobulin E therapy has been shown to be effective in preventing peanut-induced reactions but it does not result in long-term tolerance. Two important advances have recently been reported. One involves gradual oral introduction of peanut protein to desensitise, whereas the other approach uses a combination of anti-immunoglobulin E and oral peanut immunotherapy. Both approaches could offer a way to desensitise with a far greater margin of safety than has, hitherto, been reported. This article provides an overview of the literature on peanut immunotherapy and describes the experience in a small group of children in Hong Kong who were treated successfully using anti-immunoglobulin E combined with oral peanut desensitisation.

KEYWORDS:

Desensitization, immunologic; Immunoglobulin E; Peanut hypersensitivity

PMID:
24948668
DOI:
10.12809/hkmj144243
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Hong Kong Academy of Medicine Press
Loading ...
Support Center