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PLoS Biol. 2014 Jun 17;12(6):e1001882. doi: 10.1371/journal.pbio.1001882. eCollection 2014 Jun.

The billion cell construct: will three-dimensional printing get us there?

Author information

1
Department of Bioengineering, Rice University, Houston, Texas, United States of America.

Abstract

How structure relates to function--across spatial scales, from the single molecule to the whole organism--is a central theme in biology. Bioengineers, however, wrestle with the converse question: will function follow form? That is, we struggle to approximate the architecture of living tissues experimentally, hoping that the structure we create will lead to the function we desire. A new means to explore the relationship between form and function in living tissue has arrived with three-dimensional printing, but the technology is not without limitations.

PMID:
24937565
PMCID:
PMC4061004
DOI:
10.1371/journal.pbio.1001882
[Indexed for MEDLINE]
Free PMC Article

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