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Curr Biol. 2014 Jun 16;24(12):R566-R569. doi: 10.1016/j.cub.2014.05.011.

Sensory biology: it takes Piezo2 to tango.

Author information

1
Department of Physiology, The University of Tennessee Health Science Center, Memphis, TN, USA.
2
Departments of Anesthesiology, Perioperative and Pain Medicine and Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA.
3
Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA. Electronic address: mbgoodman@stanford.edu.

Abstract

A trio of papers has resolved an outstanding controversy regarding the function of Merkel cells and their afferent nerve fiber partners. Merkel cells sense mechanical stimuli (through Piezo2), fire action potentials, and are sufficient to activate downstream sensory neurons.

PMID:
24937283
DOI:
10.1016/j.cub.2014.05.011
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