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Curr Biol. 2014 Jun 16;24(12):R560-R562. doi: 10.1016/j.cub.2014.05.013.

Autophagy: close contact keeps out the uninvited.

Author information

1
Frontier Research Center, Tokyo Institute of Technology, Yokohama, Japan. Electronic address: hnakatogawa@iri.titech.ac.jp.
2
Frontier Research Center, Tokyo Institute of Technology, Yokohama, Japan. Electronic address: yohsumi@iri.titech.ac.jp.

Abstract

In selective autophagy, autophagosomes sequester specific targets to be degraded in lysosomes/vacuoles. A new study now provides critical insights into the mechanism by which the autophagosomal membrane closely sticks to the target to avoid incorporating material that should not be degraded.

PMID:
24937280
DOI:
10.1016/j.cub.2014.05.013
[Indexed for MEDLINE]
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