Send to

Choose Destination
See comment in PubMed Commons below
Rep Pract Oncol Radiother. 2013 Aug 7;19(1):62-4. doi: 10.1016/j.rpor.2013.07.004. eCollection 2014 Jan.

Mucoepidermoid carcinoma of lung masquerading as urothelial carcinoma of bladder.

Author information

Department of Medical Oncology, Mercy University Hospital, Cork, Ireland.
Department of Pathology, Cork University Hospital, Cork, Ireland.
Department of Cardiothoracic Surgery, Cork University Hospital, Cork, Ireland.
Department of Medical Oncology, Mid-Western Regional Hospital, Dooradoyle, Limerick, Ireland.



Mucoepidermoid carcinoma (MEC) of the lung is a rare subtype of non-small cell lung cancer. There is no consensus regarding optimal management for this disease.


We present a case of MEC of the lung in a 75 year-old female with a history of superficial urothelial carcinoma of the bladder. The patient was found to have an asymptomatic lung mass. Initial biopsy suggested metastatic recurrence of urothelial carcinoma and therefore, cisplatin and gemcitabine chemotherapy was administered prior to surgical resection. Pathological analysis of the resected specimen confirmed a diagnosis of stage IIIA MEC with focal high-grade features including transitional cell-like areas. Adjuvant radiotherapy was administered due to a positive microscopic resection margin. No chemotherapy was given due to lack of supporting data. The patient developed widespread metastatic disease 3 months following completion of radiotherapy and died 1 month later.


This case demonstrates the possibility of dual pathology in cases where metastatic disease is suspected. The use of small tissue samples may complicate diagnosis due to the heterogeneity of malignant tumours.


Adequate tissue; Dual pathology; Mucoepidermoid carcinoma

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center