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J Clin Hypertens (Greenwich). 2014 Aug;16(8):581-6. doi: 10.1111/jch.12361. Epub 2014 Jun 17.

Relationship of sodium and magnesium intakes to hypertension proven by 24-hour urianalysis in a South Indian population.

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Rajah Muthiah Medical College, Annamalai University, Chidambaram, India.


The Healthy Eating Asians Remain Together (HEART) study was carried out to investigate the relationship between 24-hour urine nutritional biomarkers and cardiometabolic risks in India. A total of 168 participants underwent health examination to assess body mass index, blood pressure, and 24-hour urine samples. The participants were divided into normotensive and hypertensive. The average blood pressure, weight, and body mass index were significantly high in patients considered to be hypertensive, and 24-hour urine biomarkers showed significant differences in sodium and magnesium/creatinine ratios in patients aged 40 and older. High sodium intake and reduction in magnesium consumption are associated with increased blood pressure in patients from India.

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