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J Obstet Gynaecol Can. 2014 Jun;36(6):506-9.

The fetal safety of statins: a systematic review and meta-analysis.

Author information

  • 1The Motherisk Program, Division of Clinical Pharmacology and Toxicology, Department of Pediatrics, Hospital for Sick Children, Toronto ON.

Abstract

in English, French

Although an initial case series suggested that use of statins in pregnancy carried teratogenic risk, a recent meta-analysis of controlled observational studies has failed to corroborate this. A large number of potentially beneficial uses of statins in pregnant women have prompted a new evaluation of the risk-benefit ratio of these agents in pregnancy.

KEYWORDS:

cholesterol; congenital malformations; pregnancy; statins

PMID:
24927189
[PubMed - indexed for MEDLINE]
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