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J Invest Dermatol. 2014 Jul;134(7):1791-1794. doi: 10.1038/jid.2014.33.

An unexpected role: UVA-induced release of nitric oxide from skin may have unexpected health benefits.

Author information

1
Dermatology, Bosch Institute, Sydney Cancer Centre, University of Sydney, Sydney, New South Wales, Australia. Electronic address: gary.halliday@sydney.edu.au.
2
Dermatology, Bosch Institute, Sydney Cancer Centre, University of Sydney, Sydney, New South Wales, Australia; Infectious Diseases and Immunology, Bosch Institute, Sydney Cancer Centre, University of Sydney, New South Wales, Sydney, Australia.

Abstract

UVR has deleterious and beneficial effects on human health. In this issue, Liu et al. (2014) show that UVA decreases blood pressure and increases blood flow and heart rate in humans, which is beneficial to the cardiovascular system. This is likely mediated by UVA causing release of nitric oxide (NO) from skin stores. This mediator may have additional effects on human health.

PMID:
24924758
DOI:
10.1038/jid.2014.33
[Indexed for MEDLINE]
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