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Chem Commun (Camb). 2014 Aug 4;50(60):8161-3. doi: 10.1039/c4cc03498h.

Robust detection of tyrosine phosphatase activity by coupling chymotrypsin-assisted selective peptide cleavage and a graphene oxide-based fluorescent platform.

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1
Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, Hebei Province, P. R. China.

Abstract

A versatile graphene oxide (GO)-based fluorescent assay is developed for the detection of protein tyrosine phosphatase activity by coupling with a chymotrypsin-assisted selective peptide cleavage reaction.

PMID:
24923797
DOI:
10.1039/c4cc03498h
[Indexed for MEDLINE]
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