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Structure. 2014 Jun 10;22(6):803-4. doi: 10.1016/j.str.2014.05.013.

Hopeful (protein InDel) monsters?

Author information

1
Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel.
2
Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address: tawfik@weizmann.ac.il.

Abstract

In this issue of Structure, Arpino and colleagues describe in atomic detail how a protein stomachs a deletion within a helix, an event that rarely occurs in nature or in the lab. Can insertions and deletions (InDels) trigger dramatic structural transitions?

PMID:
24918338
DOI:
10.1016/j.str.2014.05.013
[Indexed for MEDLINE]
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