Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology

Gut. 2014 Aug;63(8):1210-28. doi: 10.1136/gutjnl-2013-306578. Epub 2014 Jun 10.

Abstract

A multidisciplinary panel of 18 physicians and 3 non-physicians from eight countries (Sweden, UK, Argentina, Australia, Italy, Finland, Norway and the USA) reviewed the literature on diagnosis and management of adult coeliac disease (CD). This paper presents the recommendations of the British Society of Gastroenterology. Areas of controversies were explored through phone meetings and web surveys. Nine working groups examined the following areas of CD diagnosis and management: classification of CD; genetics and immunology; diagnostics; serology and endoscopy; follow-up; gluten-free diet; refractory CD and malignancies; quality of life; novel treatments; patient support; and screening for CD.

Keywords: Coeliac Disease; Gluten; Gluten Free Diet; Small Bowel Disease.

Publication types

  • Practice Guideline
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Biopsy
  • Celiac Disease / diagnosis*
  • Celiac Disease / diet therapy*
  • Celiac Disease / pathology
  • Diet, Gluten-Free*
  • Duodenum / pathology*
  • Endoscopy, Gastrointestinal
  • GTP-Binding Proteins
  • Gliadin / immunology
  • Histocompatibility Testing
  • Humans
  • Immunoglobulin A / blood*
  • Protein Glutamine gamma Glutamyltransferase 2
  • Transglutaminases / immunology

Substances

  • Immunoglobulin A
  • Gliadin
  • Protein Glutamine gamma Glutamyltransferase 2
  • Transglutaminases
  • GTP-Binding Proteins