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Arch Dis Child. 2014 Oct;99(10):933-6. doi: 10.1136/archdischild-2013-304727. Epub 2014 Jun 9.

An extensively hydrolysed rice protein-based formula in the management of infants with cow's milk protein allergy: preliminary results after 1 month.

Author information

1
Universitair KinderZiekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

Abstract

BACKGROUND:

Guidelines recommend extensively hydrolysed cow's milk protein formulas (eHF) in the treatment of infants diagnosed with cow's milk protein allergy (CMPA). Extensively hydrolysed rice protein infant formulas (eRHFs) have recently become available, and could offer a valid alternative.

METHODS:

A prospective trial was performed to evaluate the clinical tolerance of a new eRHF in infants with a confirmed CMPA. Patients were followed for 1 month. Clinical tolerance of the eRHF was evaluated with a symptom-based score (SBS) and growth (weight and length) was monitored.

RESULTS:

Thirty-nine infants (mean age 3.4 months, range 0.5-6 months) diagnosed with CMPA were enrolled. All infants tolerated the eRHF and experienced a normal growth.

CONCLUSIONS:

In accordance with current guidelines, this eRHF is tolerated by more than 90% of children with proven CMPA with a 95% CI, and is an adequate alternative to cow's milk-based eHF.

TRIAL REGISTRATION NUMBER:

ClinicalTrials.gov NCT01998074.

KEYWORDS:

Allergy; Gastroenterology; General Paediatrics; Nutrition

PMID:
24914098
PMCID:
PMC4173818
DOI:
10.1136/archdischild-2013-304727
[Indexed for MEDLINE]
Free PMC Article

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