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J Cosmet Dermatol. 2014 Jun;13(2):103-8. doi: 10.1111/jocd.12086.

Significant improvement in mild acne following a twice daily application for 6 weeks of an acidic cleansing product (pH 4).

Author information

1
Dr. August Wolff GmbH & Co. KG Arzneimittel, Bielefeld, Germany.

Abstract

BACKGROUND:

Cleansing products for acne should remove excessive sebum, reduce acne-related bacteria and improve inflammation.

AIMS:

The aim of the study was to investigate a topical cleansing product containing glycolic acid with pH 4 in mild acne vulgaris.

METHODS:

Sixty patients were recruited for this open uncontrolled clinical trial. The tested product was exclusively applied twice a day for 6 weeks. The efficacy was judged by a dermatologist according to the Leeds score after 3 and 6 weeks. In addition, efficacy and tolerability were judged subjectively by physician and patients.

RESULTS:

Mild acne improved significantly after 6 weeks (baseline: 0.699 vs. day 42: 0.602; P < 0.001). Efficacy and tolerability were judged better by physician as compared with patients' assessment.

CONCLUSION:

In this clinical trial, a topical cleansing product containing glycolic acid with pH 4 improved mild acne significantly following twice-daily application for 6 weeks as monotherapy.

KEYWORDS:

AHA; P. acnes; acne vulgaris; antibacterial; clinical trial; glycolic acid

PMID:
24910273
DOI:
10.1111/jocd.12086
[Indexed for MEDLINE]

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