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Int J Tuberc Lung Dis. 2014 Jul;18(7):837-9. doi: 10.5588/ijtld.13.0029.

Changes of FASH ultrasound findings in TB-HIV patients during anti-tuberculosis treatment.

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<label>*</label>Department of Medicine, Klinikum Muenchen-Perlach, Munich, Germany.
<label><sup>†</sup></label>Division of Infectious and Tropical Diseases, University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico San Matteo Hospital Foundation, Pavia.
<label><sup>‡</sup></label>Infectious and Tropical Diseases Unit, San Bortolo Hospital, Vicenza, Italy.


Ultrasound findings of extra-pulmonary tuberculosis (TB) have been well-described, particularly in human immunodeficiency virus (HIV) co-infected patients, and are often used as a basis of diagnosis in high-prevalence settings. Changes in findings during anti-tuberculosis treatment are less well documented. We present a single-centre case series of 21 TB-HIV co-infected individuals with typical ultrasound findings present at baseline. In 16/21 (76%) patients, all findings had resolved by month 3 of treatment. In patients with persistent ultrasound findings at 3 months, non-adherence, drug resistance, chronic disease, immune-reconstitution inflammatory syndrome and alternative diagnoses were identified. Follow-up ultrasound at month 3 may help identify high-risk cases.

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