Format

Send to

Choose Destination
See comment in PubMed Commons below
Acta Med Iran. 2014;52(3):197-200.

Human papilloma virus and esophageal squamous cell carcinoma.

Author information

1
Department of Pathology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. haerihay@sina.tums.ac.ir.
2
Department of Pathology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. omid_mar@yahoo.com.
3
Department of Pathology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. asadiamo@sina.tums.ac.ir.
4
Department of Pathology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Cancer Research Center, Tehran University of Medical Sciences, Tehran Iran. shahsiah@yahoo.com.

Abstract

Human papillomavirus (HPV) has also been suggested as an etiology of esophageal squamous cell carcinoma (SCC). The aim of this study was to investigate the prevalence of HPV infection in esophageal SCCs in our region with strict contamination control to prevent false positive results. Thirty cases of esophageal squamous cell carcinomas were chosen by simple random selection in a period of two years. PCR for target sequence of HPV L1 gene was performed on nucleic acid extracted from samples by means of GP5+/GP6+ primers. All tissue samples in both case and control groups were negative for HPV-DNA. Although the number of cases in this study was limited, the contribution of HPV in the substantial number of esophageal SCCs in our region is unlikely.

PMID:
24901721
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments

    Supplemental Content

    Full text links

    Icon for Tehran University of Medical Sciences, The Center for Electronic Resources Provision & Journals Development
    Loading ...
    Support Center