Performance of the Verigene Gram-negative blood culture assay for rapid detection of bacteria and resistance determinants

J Clin Microbiol. 2014 Aug;52(8):3085-7. doi: 10.1128/JCM.01099-14. Epub 2014 Jun 4.

Abstract

Nonduplicate blood cultures that were positive for Gram-negative bacilli (n = 125) were tested by the Verigene Gram-negative blood culture (BC-GN) assay; 117 (90.7%) isolates were members of the panel. For identification and resistance markers, the agreements with routine methods were 97.4% (114/117) and 92.3% (12/13). The BC-GN assay is a rapid and accurate tool for the detection of pathogens from blood cultures and could be integrated alongside conventional systems to enable faster patient management, but the clinical benefits should be further evaluated.

Publication types

  • Evaluation Study

MeSH terms

  • Bacteriological Techniques / methods*
  • Blood / microbiology*
  • Drug Resistance, Bacterial*
  • Gram-Negative Bacteria / drug effects*
  • Gram-Negative Bacteria / isolation & purification*
  • Gram-Negative Bacterial Infections / diagnosis*
  • Gram-Negative Bacterial Infections / microbiology
  • Humans
  • Molecular Diagnostic Techniques / methods*
  • Time Factors