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Otolaryngol Head Neck Surg. 2014 Sep;151(3):381-93. doi: 10.1177/0194599814536847. Epub 2014 Jun 4.

Electronic nicotine delivery systems ("e-cigarettes"): review of safety and smoking cessation efficacy.

Author information

1
Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida, USA Paul.Harrell@Moffitt.org.
2
Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida, USA.
3
Department of Otolaryngology-Head and Neck Surgery, University of South Florida College of Medicine, Tampa, Florida, USA.

Abstract

BACKGROUND AND OBJECTIVES:

Cigarette smoking is common among cancer patients and is associated with negative outcomes. Electronic nicotine delivery systems ("e-cigarettes") are rapidly growing in popularity and use, but there is limited information on their safety or effectiveness in helping individuals quit smoking.

DATA SOURCES:

The authors searched PubMed, Web of Science, and additional sources for published empirical data on safety and use of electronic cigarettes as an aid to quit smoking.

REVIEW METHODS:

We conducted a structured search of the current literature up to and including November 2013.

RESULTS:

E-cigarettes currently vary widely in their contents and are sometimes inconsistent with labeling. Compared to tobacco cigarettes, available evidence suggests that e-cigarettes are often substantially lower in toxic content, cytotoxicity, associated adverse effects, and secondhand toxicity exposure. Data on the use of e-cigarettes for quitting smoking are suggestive but ultimately inconclusive.

CONCLUSIONS:

Clinicians are advised to be aware that the use of e-cigarettes, especially among cigarette smokers, is growing rapidly. These devices are unregulated, of unknown safety, and of uncertain benefit in quitting smoking.

IMPLICATIONS FOR PRACTICE:

In the absence of further data or regulation, oncologists are advised to discuss the known and unknown safety and efficacy information on e-cigarettes with interested patients and to encourage patients to first try FDA-approved pharmacotherapies for smoking cessation.

KEYWORDS:

carcinogens; e-cigarettes; electronic nicotine delivery systems; nicotine; personal vaporizers; smoking; toxicity; vapers; vaping

PMID:
24898072
PMCID:
PMC4376316
DOI:
10.1177/0194599814536847
[Indexed for MEDLINE]
Free PMC Article

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