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Curr Biol. 2014 Jun 2;24(11):R522-4. doi: 10.1016/j.cub.2014.04.022.

Bacterial evolution: rewiring modules to get in shape.

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  • 1Department of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Room 355, Princeton, NJ 08544, USA.
  • 2Department of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Room 355, Princeton, NJ 08544, USA. Electronic address: zgitai@princeton.edu.

Abstract

Bacterial species take on a wide variety of shapes, but the mechanisms by which specific shapes evolve have remained poorly understood. A recent study demonstrates that two Asticcacaulis species repurposed an ancestral regulatory protein to rewire the modules of stalk regulation, localization, and synthesis, thereby generating new shapes.

Copyright © 2014 Elsevier Ltd. All rights reserved.

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