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Pediatr Emerg Care. 2014 Jun;30(6):427-33; quiz 434-6. doi: 10.1097/PEC.0000000000000155.

Review of the use of lipid emulsion in nonlocal anesthetic poisoning.

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1
*Associate Medical Director, Wisconsin Poison Center and †Associate Professor of Pediatrics and Emergency Medicine (Kostic); Professor of Pediatric Emergency Medicine (Gorelick), Medical College of Wisconsin, Milwaukee, WI.

Abstract

Intravenous lipid emulsion (ILE) has been used widely for the treatment of poisoning due to local anesthetic agent and is increasingly reported as a therapy for other forms of poisoning. This article will review the proposed mechanisms of action for ILE in poisoning and the evidence from animal studies and human experience supporting the use of ILE for poisoning due to nonlocal anesthetic agents.

PMID:
24892685
DOI:
10.1097/PEC.0000000000000155
[Indexed for MEDLINE]
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