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Indian J Dermatol. 2014 May;59(3):299-301. doi: 10.4103/0019-5154.131415.

Varicella zoster with erythema multiforme in a young girl: a rare association.

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Department of Dermatology, Venereology & Leprosy, Father Muller Medical College, Kankanady, Mangalore, Karnataka, India.


Erythema multiforme (EM) is an acute, self-limited, mucocutaneous disorder regarded as a hypersensitivity reaction which is triggered by various factors like infection, drugs, and food. Infectious agents are considered to be a major cause of EM other than idiopathic cause. A young girl presented with fluid-filled lesions all over the body of 3 days duration with history of similar lesions with fever in her sibling 2 weeks prior to admission. This was followed by large fluid-filled lesions with halo 3 days thereafter over the trunk, extremities suggesting target lesions of EM. The diagnosis was confirmed by cytology and positive serology. Varicella zoster virus (VZV) has rarely been reported as an etiological agent, despite its high incidence in childhood. VZV as an etiology of EM in a young girl has not been reported so far. This case was reported for its rare association of EM and varicella zoster and also for its rare presentation in a young girl.


Erythema multiforme; varicella zoster; young girl

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