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Am J Trop Med Hyg. 2014 Aug;91(2):235-9. doi: 10.4269/ajtmh.13-0742. Epub 2014 Jun 2.

Sequential episodes of dengue--Puerto Rico, 2005-2010.

Author information

1
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia; Dengue Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico tsharp@cdc.gov.
2
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia; Dengue Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.

Abstract

Of 53,633 suspected dengue cases reported to a passive dengue surveillance system in Puerto Rico during 2005-2010, 949 individuals were reported on more than one occasion and 21 had laboratory-confirmed dengue on two separate occasions. Median time between illness episodes was 2.9 years (range: 62 days-5.3 years). Seventeen (81%) individuals with sequential episodes of dengue were male, and seven (33%) were adults. All 21 individuals experienced one episode and seven (33%) individuals experienced both episodes during a large epidemic that occurred in 2010. These observations show that heterotypic dengue virus immunity that protects against illness may have considerable variability but typically does not last longer than 3 years.

PMID:
24891464
PMCID:
PMC4125242
DOI:
10.4269/ajtmh.13-0742
[Indexed for MEDLINE]
Free PMC Article
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