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FEMS Microbiol Lett. 2014 Aug;357(1):63-8. doi: 10.1111/1574-6968.12489. Epub 2014 Jul 10.

DBAASP: database of antimicrobial activity and structure of peptides.

Author information

1
Laboratory of Bioinformatics, Ivane Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia.

Abstract

The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is a manually curated database for those peptides for which antimicrobial activity against particular targets has been evaluated experimentally. The database is a depository of complete information on: the chemical structure of peptides; target species; target object of cell; peptide antimicrobial/haemolytic/cytotoxic activities; and experimental conditions at which activities were estimated. The DBAASP search page allows the user to search peptides according to their structural characteristics, complexity type (monomer, dimer and two-peptide), source, synthesis type (ribosomal, nonribosomal and synthetic) and target species. The database prediction algorithm provides a tool for rational design of new antimicrobial peptides. DBAASP is accessible at http://www.biomedicine.org.ge/dbaasp/.

KEYWORDS:

antimicrobial activity; antimicrobial peptide; database; haemolytic/cytotoxic activity

PMID:
24888447
DOI:
10.1111/1574-6968.12489
[Indexed for MEDLINE]
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