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Nat Commun. 2014 Jun 2;5:4044. doi: 10.1038/ncomms5044.

A Gondwanan imprint on global diversity and domestication of wine and cider yeast Saccharomyces uvarum.

Author information

1
1] Centro de Recursos Microbiológicos, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal [2].
2
Centro de Recursos Microbiológicos, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
3
Laboratorio de Microbiología Aplicada y Biotecnología, Instituto de Investigaciones en Biodiversidad y Medio-ambiente, INIBIOMA (CONICET-UNComahue), 8400 Bariloche, Argentina.
4
Laboratory of Genetics, Genome Center of Wisconsin, Wisconsin Energy Institute, DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
5
Bordeaux Sciences agro, EA Œnologie 4577, ISVV, Villenave d'Ornon F-33882, France.
6
University Bordeaux, EA Œnologie 4577, ISVV, Villenave d'Ornon F-33882, France.
7
CNRS UMR 5800, University Bordeaux, INRIA project-team Magnome, Talence F33400, France.
8
1] University Bordeaux, EA Œnologie 4577, ISVV, Villenave d'Ornon F-33882, France [2] BIOLAFFORT, Bordeaux F-33072, France.

Abstract

In addition to Saccharomyces cerevisiae, the cryotolerant yeast species S. uvarum is also used for wine and cider fermentation but nothing is known about its natural history. Here we use a population genomics approach to investigate its global phylogeography and domestication fingerprints using a collection of isolates obtained from fermented beverages and from natural environments on five continents. South American isolates contain more genetic diversity than that found in the Northern Hemisphere. Moreover, coalescence analyses suggest that a Patagonian sub-population gave rise to the Holarctic population through a recent bottleneck. Holarctic strains display multiple introgressions from other Saccharomyces species, those from S. eubayanus being prevalent in European strains associated with human-driven fermentations. These introgressions are absent in the large majority of wild strains and gene ontology analyses indicate that several gene categories relevant for wine fermentation are overrepresented. Such findings constitute a first indication of domestication in S. uvarum.

PMID:
24887054
PMCID:
PMC5081218
DOI:
10.1038/ncomms5044
[Indexed for MEDLINE]
Free PMC Article
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