Stroke survivors over-estimate their medication self-administration (MSA) ability, predicting memory loss

Brain Inj. 2014;28(10):1328-33. doi: 10.3109/02699052.2014.915984. Epub 2014 Jun 2.

Abstract

Background and objective: Medication self-administration (MSA) may be cognitively challenging after stroke, but guidelines are currently lacking for identifying high-functioning stroke survivors who may have difficulty with this task. Complicating this matter, stroke survivors may not be aware of their cognitive problems (cognitive anosognosia) and may over-estimate their MSA competence. The authors wished to evaluate medication self-administration and MSA self-awareness in 24 consecutive acute stroke survivors undergoing inpatient rehabilitation, to determine if they would over-estimate their medication self-administration and if this predicted memory disorder.

Methods: Stroke survivors were tested on the Hopkins Medication Schedule and also their memory, naming mood and dexterity were evaluated, comparing their performance to 17 matched controls.

Results: The anosognosia ratio indicated MSA over-estimation in stroke survivors compared with controls--no other over-estimation errors were noted relative to controls. A strong correlation was observed between over-estimation of MSA ability and verbal memory deficit, suggesting that formally assessing MSA and MSA self-awareness may help detect cognitive deficits.

Conclusions: Assessing medication self-administration and MSA self-awareness may be useful in rehabilitation and successful community-return after stroke.

Keywords: Anosognosia; memory; patient safety; rehabilitation; stroke.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Agnosia / physiopathology
  • Agnosia / psychology*
  • Female
  • Humans
  • Male
  • Memory Disorders / psychology*
  • Middle Aged
  • Neuropsychological Tests
  • Self Administration / psychology*
  • Self Administration / statistics & numerical data
  • Self Care / psychology*
  • Stroke / physiopathology
  • Stroke / psychology*
  • Stroke Rehabilitation
  • Survivors / psychology*